Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or "knocked out", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.
An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMOs were bacteria generated in 1973 and GM mice in 1974. Insulin-producing bacteria were commercialized in 1982 and genetically modified food has been sold since 1994. GloFish, the first GMO designed as a pet, was first sold in the United States in December 2003.
A noun (from Latinnōmen, literally meaning "name") is a word that functions as the name of some specific thing or set of things, such as living creatures, objects, places, actions, qualities, states of existence, or ideas.Linguistically, a noun is a member of a large, openpart of speech whose members can occur as the main word in the subject of a clause, the object of a verb, or the object of a preposition.
Lexical categories (parts of speech) are defined in terms of the ways in which their members combine with other kinds of expressions. The syntactic rules for nouns differ from language to language. In English, nouns are those words which can occur with articles and attributive adjectives and can function as the head of a noun phrase.
Word classes (parts of speech) were described by Sanskrit grammarians from at least the 5th century BC. In Yāska's Nirukta, the noun (nāma) is one of the four main categories of words defined.